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Saturday, August 1, 2020 | History

5 edition of Hepatitis B virus antigens in tissues found in the catalog.

Hepatitis B virus antigens in tissues

by M. B. Ray

  • 195 Want to read
  • 19 Currently reading

Published by University Park Press in Baltimore .
Written in English

    Subjects:
  • Hepatitis B -- Diagnosis.,
  • Hepatitis associated antigen -- Analysis.,
  • Liver -- Biopsy.,
  • Cytodiagnosis.,
  • Hepatitis B antigens -- Analysis.

  • Edition Notes

    Includes bibliographies and index.

    Statementby M. B. Ray.
    Classifications
    LC ClassificationsRC848.H44 R38
    The Physical Object
    Paginationx, 165 p. :
    Number of Pages165
    ID Numbers
    Open LibraryOL4403400M
    ISBN 100839114257
    LC Control Number79004867
    OCLC/WorldCa4983551

    Hepatitis B surface antigen (HBsAg) is the first marker of HBV detectable in serum in acute infection. By the time clinical and biochemical hepatitis is present after an incubation period of up to days, other serologic markers of HBV infection appear—including antibody to HBV core antigen (anti-HBc). HBxAg, expressed independently of other viral antigens, indicates integration of this segment of the viral genome into the host genome. Its presence in hepatocellular carcinoma cells from chronic hepatitis B patients, in the absence of the other HBV antigens, suggests an important role in hepatocarcinogenesis mediated by numerous possible.

    Hepatitis B Virus DNA. Hepatitis B virus DNA in serum is a marker of viremia and infectivity. Currently available polymerase chain reaction (PCR) assays are highly sensitive with detection limits of less than 20 IU/mL and a range of linearity up to between 8 log 10 IU/mL and 9 log 10 IU/mL. Using these sensitive assays, HBV DNA can be detected. The expression of hepatitis B virus antigens was studied by double staining liver tissue with appropriate antisera and correlated with serum hepatitis B viral DNA and histology in 28 patients with.

    confidenceinterval, 12 to ).Hepatitis B vaccination and hepatitis B immune Because there is a high risk of acquiring HBV from a needlestick injury, 13 health care profession-. Hepatitis B virus antigens in primary hepatic carcinoma: Immunofluorescent techniques on fixed liver tissue Article (PDF Available) in Journal of Clinical Pathology 31(12) January


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Hepatitis B virus antigens in tissues by M. B. Ray Download PDF EPUB FB2

A tremendous new impetus was given to hepatitis research by Baruch Blumberg's discovery of his 'Australia Antigen', now known as hepatitis B surface antigen. This led to an unheard-of outburst of research activity to elucidate the nature of the virus, its chemical and antigenic composition, its epidemiology, and pathogenetic mechanisms in the.

Get this from a library. Hepatitis B Virus Antigens in Tissues. [M B Ray] -- Ever since the emergence of the concept of catharral jaundice by Virchow, viral hepatitis has eluded scientists as a pathogenetic enigma. A tremendous new impetus was given to hepatitis research by.

Hepatitis B virus antigens in tissues. [M B Ray] Home. WorldCat Home About WorldCat Help. Search. Search for Library Items Search for Lists Search for Contacts Search for a Library.

Create Book: All Authors / Contributors: M B Ray. Find more information about: ISBN: X: OCLC Number: Hepatitis B virus antigens in tissues. [M B Ray] Home. Hepatitis B virus antigens in tissues book Home About WorldCat Help.

Search. Search for Library Items Search for Lists Search for Contacts Search for a Library. Create Book: All Authors / Contributors: M B Ray. Find more information about: ISBN: OCLC Number: Hepatitis B virus markers were demonstrated in non-neoplastic tissue, mainly in patients with a well-differentiated carcinoma, and only in these cases were they found also in the neoplastic tissue.

These results show that hepatitis B virus antigens, including HBcAg, can be detected in the neoplastic cells of well-differentiated carcinoma of the.

Aim: To study the intrahepatic expression of hepatitis B surface antigen (HBsAg) and hepatitis B core antigen (HBcAg) in chronic hepatitis B patients with and without hepatocellular carcinoma.

Methods: A total of 33 chronic hepatitis B patients (mean age of ± years), comprising of 14 HBeAg positive and 19 HBeAg negative patients; and 13 patients with hepatitis B virus related.

Core tip: This study described the distributions and patterns of intrahepatic hepatitis B core antigen and hepatitis B surface antigen (HBsAg) in patients with chronic hepatitis B using a novel, modified classification system.

The HBeAg negative patients were found to have intense HBsAg in liver tissues despite their lower serum hepatitis B virus (HBV) DNA levels. Keywords: Hepatitis B virus surface antigen, Hepatitis C virus antigen, Histological activity index, Immunohisto-chemistry, Hepatocellular carcinoma, Alpha-fetoprotein.

INTRODUCTION Hepatocellular carcinoma (HCC) is one of the most common malignant tumors worldwide[ 1, 2 ]. HBsAg is the antigen used to make hepatitis B vaccine. Hepatitis B surface antibody (anti-HBs): The presence of anti-HBs is generally interpreted as indicating recovery and immunity from hepatitis B virus infection.

Anti-HBs also develops in a person who has been successfully vaccinated against hepatitis B. Total hepatitis B core. Increasing evidence suggests that a link exists between hepatitis B virus (HBV) serum markers and pancreatic cancer (PC).

In this study, HBsAg and HBcAg were expressed in % (34/) of PC and % (47/) of non-tumor pancreatic tissues, and they were significantly associated with chronic pancreatitis (P = ).The HBV S, C and X genes were identified in 20% (6/30) of PC and.

Chimeric antigen receptor (CAR) T cell therapy is a promising novel therapeutic approach for cancer but also for chronic infection. We have developed a fully human, second-generation CAR directed against the envelope protein of hepatitis B virus on the surface of infected cells (S-CAR).

Association of human hepatocellular carcinoma and cirrhosis with hepatitis B virus surface and core antigens in the liver. Int J Cancer. Nov 15; 20 (5)– Prince AM, Brotman B, Jass D, Ikram H. Specificity of the direct solid-phase radioimmunoassay for detection of hepatitis-B antigen. Lancet.

Jun 16; 1 ()– The logarithmic growth of publications on the subject of viral hepatitis since the discovery of Australia antigen (hepatitis B surface antigen) as one of the specific markers of infection with hepatitis B virus is probably unprecedented and reflects the impact which these infections have on every aspect of medical practice.

One of the key questions in hepatology is the relationship between Cited by:   More than 2 million human tissue transplants (bone, tendon, cartilage, skin, cornea, amniotic membrane, stem cells, heart valve, blood vessel, etc.), are performed worldwide every and tissues are shared between countries which have different regulations and laboratory equipment and represent a risk of hepatitis B virus (HBV) transmission that has become a global.

Hepatitis B core antigen (HBcAg) and hepatitis B surface antigen (HBsAg) were localized in human liver tissues by the peroxidase-labeled antibody method at the light and electron microscopic levels. In large measure, a compilation of the author's published and unpublished studies of the localization of hepatitis B virus antigens in tissues.

The chapters written in the format of individual papers include studies in human liver disease, experimental hepatitis, the effect of interferon, and in hepatitis-associated glomerulonephritis. Ling, C. and Overby, L. Prevalence of hepatitis B virus antigen as revealed Ray M.B.

() Hepatitis B surface antigen in the liver and serum of patients with hepatitis. In: Hepatitis B Virus Antigens in Tissues.

Springer, Dordrecht Print ISBN ; Online ISBN ; eBook Packages Springer Book. Hepatitis B is an infectious disease caused by the hepatitis B virus (HBV) that affects the liver; it is a type of viral hepatitis.

It can cause both acute and chronic infection. Many people have no symptoms during the initial infection. In acute infection, some may develop a rapid onset of sickness with vomiting, yellowish skin, tiredness, dark urine and abdominal pain.

Background & aims: Chronic infection with hepatitis B virus (HBV) progresses through different phases. The first, called the immune-tolerant phase, has been associated with a lack of disease activity. We examined HBV-DNA integration, clonal hepatocyte expansion, HBV antigen expression, and HBV-specific immune responses in patients in the immune-tolerant phase to assess whether this.

Chronic infection with the hepatitis B virus (HBV) is a major risk factor for development of hepatocellular carcinoma (HCC). The pathogenesis of cancer in HBV infection has been extensively analyzed, and multiple factors appear to play a role. A major factor is chronic inflammation and the effects o.

Background: Previous studies have revealed that hepatitis B virus (HBV) infection may be related to rheumatoid arthritis (RA), but there are no studies on the presence of HBV antigens or nucleic acid in synovium from patients with RA with HBV infection.

In the present study, we investigated the presence of HBV in the synovium and its clinical significance in RA.Abstract.

The distinctive localization patterns of HBsAg and HBcAg obtained in various types of hepatitis B were described in Chapter 4. The factors responsible for this distinctive expression of HBV components and the ultimate development of various histological types of hepatitis B remain obscure.Background: Fresh-frozen plasma (FFP) may contain antibodies to hepatitis B surface antigen (HBsAg, anti-HBs).

These anti-HBs may lead to a misinterpretation of the actual hepatitis B immune status. Furthermore, they may not only confer protection against hepatitis B virus (HBV), but may also favor the selection of HBsAg mutants.